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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC23 All Species: 10
Human Site: S421 Identified Species: 36.67
UniProt: Q5W5X9 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5W5X9 NP_001035745.1 447 50009 S421 A S K P R Q A S K A K V A F C
Chimpanzee Pan troglodytes XP_001137822 447 49909 S421 A S K P K Q A S K A K V A F C
Rhesus Macaque Macaca mulatta XP_001101066 447 49930 S421 A A K P R Q A S K A K V V L C
Dog Lupus familis XP_545827 512 57216 S438 G Q K E K A T S I L R E S L E
Cat Felis silvestris
Mouse Mus musculus Q8CHY7 488 54590 V463 A G K S R Q S V K A K V A F C
Rat Rattus norvegicus Q4V7F0 446 50253 L421 P V K S K Q S L K A K T A F C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508409 386 43077 L361 K Q S S K E R L A N K A K P P
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 94.6 67.1 N.A. 68.4 72.2 N.A. 50.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.8 96.1 74.6 N.A. 77.2 83.8 N.A. 63.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 80 13.3 N.A. 73.3 53.3 N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 86.6 33.3 N.A. 80 66.6 N.A. 20 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 58 15 0 0 0 15 43 0 15 72 0 15 58 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 72 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 15 0 15 0 0 0 0 0 15 0 0 15 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 58 0 % F
% Gly: 15 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % I
% Lys: 15 0 86 0 58 0 0 0 72 0 86 0 15 0 0 % K
% Leu: 0 0 0 0 0 0 0 29 0 15 0 0 0 29 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 15 0 0 0 0 0 % N
% Pro: 15 0 0 43 0 0 0 0 0 0 0 0 0 15 15 % P
% Gln: 0 29 0 0 0 72 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 43 0 15 0 0 0 15 0 0 0 0 % R
% Ser: 0 29 15 43 0 0 29 58 0 0 0 0 15 0 0 % S
% Thr: 0 0 0 0 0 0 15 0 0 0 0 15 0 0 0 % T
% Val: 0 15 0 0 0 0 0 15 0 0 0 58 15 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _